Johan W Jonker Selected Research

Pharmaceutical Preparations

5/2005	Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2).
5/2005	Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver.
1/2005	Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and transport of cimetidine.
11/2002	The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

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Johan W Jonker Research Topics

Disease

13	Breast Neoplasms (Breast Cancer) 06/2007 - 11/2002
9	Non-alcoholic Fatty Liver Disease 01/2022 - 02/2016
9	Insulin Resistance 01/2022 - 09/2014
6	Inflammation (Inflammations) 01/2022 - 02/2016
6	Type 2 Diabetes Mellitus (MODY) 01/2022 - 08/2002
5	Fatty Liver 01/2022 - 09/2014
5	Neoplasms (Cancer) 01/2021 - 10/2003
4	Cholestasis 12/2020 - 01/2009
4	Obesity 10/2020 - 07/2015
3	Hypercholesterolemia 01/2022 - 01/2019
3	Weight Gain 05/2021 - 09/2014
3	Hyperbilirubinemia 01/2021 - 01/2019
3	Metabolic Diseases (Metabolic Disease) 10/2020 - 01/2015
3	Cystic Fibrosis (Mucoviscidosis) 01/2019 - 01/2019
2	Fibrosis (Cirrhosis) 01/2022 - 01/2021
2	Disease Progression 01/2022 - 01/2021
2	Alzheimer Disease (Alzheimer's Disease) 03/2021 - 01/2019
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 12/2016
2	Liver Diseases (Liver Disease) 12/2020 - 01/2019
2	Dyslipidemias (Dyslipidemia) 01/2019 - 12/2017
2	Erythropoietic Protoporphyria 05/2016 - 06/2007
2	Phototoxic Dermatitis (Phototoxicity) 06/2007 - 11/2002
1	Prostatic Neoplasms (Prostate Cancer) 01/2022
1	Hepatocellular Carcinoma (Hepatoma) 01/2022
1	Inborn Errors Metabolism (Inborn Errors of Metabolism) 01/2022
1	Hyperlipidemias (Hyperlipidemia) 01/2022
1	Body Weight (Weight, Body) 01/2021
1	Hypoglycemia (Reactive Hypoglycemia) 01/2021
1	Neonatal Hyperbilirubinemia 01/2021
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 12/2020
1	Muscular Diseases (Myopathy) 12/2020
1	Dysbiosis 01/2020
1	Exocrine Pancreatic Insufficiency 01/2019
1	Weight Loss (Weight Reduction) 01/2019

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2002
7	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 09/2014
6	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 07/2012
5	LipidsIBA 01/2022 - 01/2019
5	CholesterolIBA 01/2021 - 07/2012
5	Adenosine Triphosphate (ATP)IBA 12/2016 - 11/2002
4	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 12/2017
4	Insulin (Novolin)FDA Link 01/2021 - 09/2014
4	Pharmaceutical PreparationsIBA 05/2005 - 11/2002
3	LigandsIBA 01/2022 - 07/2012
3	BilirubinIBA 01/2021 - 07/2012
3	CarcinogensIBA 01/2006 - 10/2003
2	Adenosine Triphosphatases (ATPase)IBA 01/2022 - 12/2020
2	LipopolysaccharidesIBA 01/2022 - 05/2006
2	Serine (L-Serine)FDA Link 05/2021 - 10/2017
2	Liver X ReceptorsIBA 01/2021 - 01/2019
2	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2021 - 07/2012
2	CarbohydratesIBA 01/2021 - 07/2007
2	obeticholic acidIBA 01/2021 - 01/2021
2	fibroblast growth factor 21IBA 01/2021 - 02/2020
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2019 - 01/2015
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 07/2012
2	Fibroblast Growth Factor 1 (FGF-1)IBA 02/2016 - 09/2014
2	SteroidsIBA 05/2013 - 01/2005
2	CorticosteroneIBA 05/2013 - 12/2011
2	Hormones (Hormone)IBA 05/2013 - 01/2005
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2009 - 05/2005
2	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 01/2005 - 10/2003
2	BiguanidesIBA 04/2003 - 08/2002
2	Hypoglycemic Agents (Hypoglycemics)IBA 04/2003 - 08/2002
2	Metformin (Glucophage)FDA LinkGeneric 04/2003 - 08/2002
1	Androgen Receptors (Androgen Receptor)IBA 01/2022
1	ApolipoproteinsIBA 01/2022
1	Lipoproteins (Lipoprotein)IBA 01/2022
1	Lipase (Acid Lipase)FDA Link 01/2022
1	Oleic Acid (Oleate)IBA 01/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	EnzymesIBA 01/2022
1	Peroxidase (Myeloperoxidase)IBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Apolipoproteins B (ApoB)IBA 01/2022
1	VLDL LipoproteinsIBA 01/2022
1	Phospholipases (Phospholipase)IBA 01/2022
1	Palmitic Acid (Hexadecanoic Acid)IBA 01/2022
1	Amyloid (Amyloid Fibrils)IBA 03/2021
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2021
1	T0901317IBA 01/2021
1	Ezetimibe (Zetia)FDA Link 01/2021
1	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 01/2021
1	Vitamin A (Retinol)FDA LinkGeneric 01/2021
1	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 12/2020
1	LDL CholesterolIBA 12/2020
1	Transaminases (Aminotransferases)IBA 12/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 12/2020
1	PegbelferminIBA 02/2020
1	Triglycerides (Triacylglycerol)IBA 01/2020
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020
1	MucinsIBA 01/2020
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2019
1	FructoseIBA 01/2019
1	ivacaftorIBA 01/2019
1	LaxativesIBA 01/2019

Therapy/Procedure

2	Therapeutics 01/2021 - 09/2014
2	Protein-Restricted Diet (Diet, Protein Restricted) 01/2021 - 12/2016
2	Phototherapy (Light Therapy) 01/2021 - 01/2019
1	Castration 01/2022